Aspartate aminotransferase. Determination of the active site occupancy pattern indicates independent transamination of the two subunits.
نویسندگان
چکیده
منابع مشابه
Coenzyme active site occupancy as an indicator of independence of the subunits of mitochondrial aspartate aminotransferase.
The enzyme, aspartate aminotransferase, is a dimer consisting of two identical subunits which contain overlapping subunit regions ( Eichele , G., Ford, G.C., Glor , M., Jansonius , J.N., Mavrides , C., and Christen , P. (1979) J. Mol. Biol. 133, 161-180), suggesting the possibility of subunit interactions. The structurally similar cytosolic isozyme exhibits noncooperative binding of pyridoxal 5...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1977
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(17)40098-6